Alpha Diagnostic International, Inc. Rat EAAT4 Control/blocking peptide #1 EAAT41-P

Rat EAAT4 Control/blocking peptide #1 General Information Glutamate is the main excitatory neurotransmitter in the brain. To date five glutamate Transporters have been cloned: GLAST (EAAT1), GLT1 (EAAT2), EAAC1 (EAAT3), EAAT4, and EAAT5. These transporters are believed to be critical in reducing potentially t SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 21-aa peptide from rat EAAT4 (1); Designation ( EAAT41-P, control/blocking peptide) conjugated to KLH. Epitope location ~ C-terminus, Cytoplasmic domain SpCrossreactivity The EAAT41-P peptide was found unique to EAAT4 without significant homology to other glutamate transporters. It is 95% homologous in Mouse, 90% in human and 85% in dog EAAT4. Antibody crossreactivity in various species is not established. For research use only, not for diagnostic or therapeutic use.