Alpha Diagnostic International, Inc. Human DNA Polymerase Delta, catalytic subunit (Pol D) Control/blocking peptide DNPD11-P

Human DNA Polymerase Delta, catalytic subunit (Pol D) Control/blocking peptide General Information Reactive oxygen species (H2O2?, OH?, O2, HOCL) generated during normal cellular activities or by ionizing radiation and by many oxidizing/alkylating agents can induce a wide variety of lesions in DNA ranging from oxidized bases (8-oxoguanine and thymine g SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen A 21-aa peptide sequence (designated DNPD11-P, control or blocking peptide) mapping near the N-terminus of human Pol D (1) was synthesized, coupled to KLH SpCrossreactivity The DNPD11-P peptide sequence is conserved in various species Pol : hamster, rat (100%), mouse (95%), bovine (90%), drosophila (80%), Soybean (76%), and yeast (61%). Antibody crossreactivity in various species is not experimentally verified. DNPD11-P has no significant sequence homology with other DNA polymerases. For research use only, not for diagnostic or therapeutic use.