Alpha Diagnostic International, Inc. Human Deoxyribonuclease II (Dnase II) Control/blocking peptide # 1 DNASE21-P

Human Deoxyribonuclease II (Dnase II) Control/blocking peptide # 1 General Information Deoxyribonuclease II (Dnase II, EC.3.1.22.1) is one of the two Dnase present in mammalian tissues and biological fluids. Dnase II hydrolyzes DNA to 3?-phosphoryl oligonucleotides under acidic conditions. Dnase II is also known as ?acid Dnase?. It has p SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen A 14-aa peptide (designated DNASE21-P, control/blocking peptide) near the C-terminus of human Dnase II (1) was synthesized, coupled to KLH SpCrossreactivity The DNASE21-P peptide sequence is not well conserved in mouse Dnase II. We recommend the use of DNASE22-A for the study of mouse Dnase II. DNASE21-P has no significant sequence homology with other lysosomal enzymes. Control peptide, because of its low mol. Wt (<3 kDa), is not suitable for Western. It should be used for ELISA or antibody blocking experiments For research use only, not for diagnostic or therapeutic use.