Alpha Diagnostic International, Inc. Anti-Human Deoxyribonuclease II (Dnase II) IgG #1, aff pure DNASE21-A

Anti-Human Deoxyribonuclease II (Dnase II) IgG #1, aff pure General Information Deoxyribonuclease II (Dnase II, EC.3.1.22.1) is one of the two Dnase present in mammalian tissues and biological fluids. Dnase II hydrolyzes DNA to 3?-phosphoryl oligonucleotides under acidic conditions. Dnase II is also known as ?acid Dnase?. It has p SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen A 14-aa peptide (designated DNASE21-P, control/blocking peptide) near the C-terminus of human Dnase II (1) was synthesized, coupled to KLH SpCrossreactivity The DNASE21-P peptide sequence is not well conserved in mouse Dnase II. We recommend the use of DNASE22-A for the study of mouse Dnase II. DNASE21-P has no significant sequence homology with other lysosomal enzymes. Control peptide, because of its low mol. Wt (<3 kDa), is not suitable for Western. It should be used for ELISA or antibody blocking experiments For research use only, not for diagnostic or therapeutic use.