Alpha Diagnostic International, Inc. Anti-Human Dopamine Receptor 2 (D2R) (L/S) IgG # 3, aff pure D2R13-A

Anti-Human Dopamine Receptor 2 (D2R) (L/S) IgG # 3, aff pure General Information Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of at least 5 Dopamine Receptors (DR) genes, D1-D5, have been ide SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 28-aa peptide of Human D2R ; Designated (D2R13-P or control peptide /blocking peptide) conjugated to KLH. Epitope location. ~ N-terminal, Cytoplasmic SpCrossreactivity Human D2R13-P peptide was specific for D2R. No significant sequence homology is seen with other dopamine receptors (D1 and D3-D5). It is 100% homologous with human/bovine/dog, and 50% with Xenopus D2 receptors. Antibodies generated to the human sequence have been shown to recognize the canine D2R (2). Antibody crossreactivity with D2 receptors from various species is not known. For research use only, not for diagnostic or therapeutic use.