Alpha Diagnostic International, Inc. Anti-Rat Dopamine Receptor 2 (D2R) (L) Antiserum # 2 D2R12-S

Anti-Rat Dopamine Receptor 2 (D2R) (L) Antiserum # 2 General Information Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of at least 5 Dopamine Receptors (DR) genes, D1-D5, have been ide SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 27aa peptide of rat D2RL ; Designated (D2R12-P or control peptide). Epitope location ~ N-terminal, Cytoplasmic SpCrossreactivity The 27 AA rat D2RL peptide was found only in the D2 long form. No significant sequence homology is seen with other dopamine receptors (D1, D2 short, and D3-D5). The 27 AA rat D2RL peptide shows sequence homology of 96% with human/ bovine/ dog, 64% with Xenopus D2L receptors. Antibodies generated to the rat sequence have been shown to recognize the canine D2R (2). Antibody crossreactivity with D2L receptors from various species is not known For research use only, not for diagnostic or therapeutic use.