Alpha Diagnostic International, Inc. Rat Connexin 46 (Cx46) Control/blocking peptide #1 Cx46-P

Rat Connexin 46 (Cx46) Control/blocking peptide #1 General Information Gap junctions are composed of transmembrane channels that link the cytoplasm of neighboring cells. They differ from other membrane channels since they exist between two cells. Gap junctions are relatively non-specific and allow passive diffusion of smal SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 11-aa peptide from rat Cx46 (1); Designation (Cx46-P, control/blocking peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity Rat Cx46-P immunogenic peptide sequence is specific for Cx46 and no significant homology is seen with other Connexins. CX46_p is 91% conserved in mouse and <50% in human CX46. Antibody crossreactivity in various other species is not established For research use only, not for diagnostic or therapeutic use.