Alpha Diagnostic International, Inc. Anti-Human Connexin 45 (Cx45) antiserum #2 Cx45B12-S

Anti-Human Connexin 45 (Cx45) antiserum #2 General Information Gap junctions are composed of transmembrane channels that link the cytoplasm of neighboring cells. They differ from other membrane channels since they exist between two cells. Gap junctions are relatively non-specific and allow passive diffusion of smal SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 14aa peptide of Human CX45 ; Designated (CX45B12-P or control peptide). Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity The human Cx45B12-P peptide sequence is 100% conserved in canine, 92% in mouse, and 77% in chicken Cx45 (4). It has no significant homology with other Connexins. Antibody crossreactivity with Cx45 in various species is not established. For research use only, not for diagnostic or therapeutic use.