Alpha Diagnostic International, Inc. Human Cyclooxygenase 3 (Cox-3) Control/blocking peptide # 2 COX32-P

Human Cyclooxygenase 3 (Cox-3) Control/blocking peptide # 2 General Information COX3 and PCOX1a are made from the COX1 gene but retain intron 1 in their mRNAs. PCOX-1b (53 kDa) lacks the intron 1. This intron introduces an insertion of 30-34aa, depending on mammalian species, into hydrophobic signal peptide that directs COX1 into th SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 12-aa peptide of Human COX3 (1); Designated (COX32-P or control peptide) conjugated to KLH; epitope location ~ N-terminus SpCrossreactivity COX32-P control peptide is 100% conserved in Human and dog COX3 and PCOX1a proteins. Antibody (cat # COX32-A) cross-reactivity in various species is not known. For research use only, not for diagnostic or therapeutic use.