Alpha Diagnostic International, Inc. Anti-Rat Cyclic Nucleotide Gated Channel 2 (CNG2) Antiserum #2 CNG22-S

Anti-Rat Cyclic Nucleotide Gated Channel 2 (CNG2) Antiserum #2 General Information CNG2 or OCNC1 (rat/mouse/rabbit 664 aa, bovine 663 aa) is primarily expressed in olfactory sensory neurons. It is ~80% homologous with CNG1. Unlike CNG1, CNG2 is activated both by cAMP and cGMP. Another cGMP-gated channel called CNG3 (mouse 537 aa, rat SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 19aa peptide of rat/ mouse CNG2 ; Designated (CNG22-P or control peptide /blocking peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity Rat CNG22-P control peptide is 90% conserved in mouse, 83% in rabbit and 72% in bovine CNG2. No significant sequence homology is detected with other CNGs. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.