Alpha Diagnostic International, Inc. Rat Cyclic Nucleotide Gated Channel 2 (CNG2) Control/blocking peptide # 2 CNG22-P

Rat Cyclic Nucleotide Gated Channel 2 (CNG2) Control/blocking peptide # 2 General Information CNG2 or OCNC1 (rat/mouse/rabbit 664 aa, bovine 663 aa) is primarily expressed in olfactory sensory neurons. It is ~80% homologous with CNG1. Unlike CNG1, CNG2 is activated both by cAMP and cGMP. Another cGMP-gated channel called CNG3 (mouse 537 aa, rat SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 19aa peptide of rat/ mouse CNG2 ; Designated (CNG22-P or control peptide /blocking peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity Rat CNG22-P control peptide is 90% conserved in mouse, 83% in rabbit and 72% in bovine CNG2. No significant sequence homology is detected with other CNGs. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.