Alpha Diagnostic International, Inc. Human Clock Control/blocking peptide # 2 CLO12-P

Human Clock Control/blocking peptide # 2 General Information Mouse Clock encodes a transcription factor, a single polypeptide chain of 855 aa (predicted calculated mol wt ~97 kDa; pI 6.52; hClock, 846 aa). Clock is abundantly expressed in brain (SCN, pyrifom cortex, hippocampus) as well as in other tissues (eye, to SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 20-aa peptide of human Clock (protein accession #, refs 1) ; Designated (CLO12-P or control peptide) conjugated to KLH; epitope location ~ C-terminus SpCrossreactivity The CLO12-P peptide sequence is 90% conserved in mouse/ rat, 80% in Japanese quail, chicken, and 75% in frog clock protein. No significant homology is seen with PER or other known proteins. Antibody cross-reactivity with Per1 from other species is not known For research use only, not for diagnostic or therapeutic use.