Anti-Human Calcitonin Gene Related Peptide (CGRP) antiserum #1
General Information
The calcitonin family of bioactive peptides comprises of calcitonin, amylin, two calcitonin-gene related peptides (CGRP1, and CGRP2) and adrenomedullin (ADM). Calcitonin is 32 aa peptide found in the parafollicular ?C? cells of the thyroid in mammals. I
SugApplications
Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the
SugSecAntibodies
http://4adi.com/comm
SpeciesReactivity
Human
SugNegativeControl
Non-immune Rabbit IgG Cat# 20009-1
Form
Antiserum Unpurified
SugPositiveControl
Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid
Antigen
19-aa peptide of Human CGRP/CALCA (protein accession # P10092, refs 1; Designated (CGRP11-P or control peptide) near the N-terminus
SpCrossreactivity
The human CGRP11-P is quite conserved in various species: equine, sheep, pig, canine, rat, mouse, bovine, frog, monkey, chicken, zebra fish (84-95%). There is just 1 aa change between the human CGRP1 and CGRP2. Significant sequence homology is also found with amylin. However, no significant sequence homology is detected with calcitonin or adrenomedullin. Antibody cross-reactivity in various species has not been studied
For research use only, not for diagnostic or therapeutic use.
| Alpha Diagnostic International, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | CGRP11-S |
| Product Name | Anti-Human Calcitonin Gene Related Peptide (CGRP) antiserum #1 |
