Alpha Diagnostic International, Inc. Rat Cannabinoid receptor (CB2) Control/blocking peptide # 2 CB22-P

Rat Cannabinoid receptor (CB2) Control/blocking peptide # 2 General Information CB2 (rat 410 aa, mouse 347aa, human 360 aa; ~45% homology with CB1) also inhibit adenylate cyclase activity via a pertussis toxin-sensitive G-protein. Unlike CB1, CB2 does not modulate the activity of either Q-type Ca2+ or inwardly rectifying K+ channels SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen An 18 aa peptide (designated CB22-P control peptide) Cytoplasmic Epitope location ~C-terminus of rat CB2 (1) SpCrossreactivity The rat CB22-P peptide sequence is 83% conserved in mouse, and 82% in human CB2. No significant sequence homology exists with CB1. Antibody crossreactivity in various species is not established For research use only, not for diagnostic or therapeutic use.