Alpha Diagnostic International, Inc. Anti-Human Caspase 9 (ICE9/Pro-Mch6) p35 subunit antiserum #1 CASP91-S

Anti-Human Caspase 9 (ICE9/Pro-Mch6) p35 subunit antiserum #1 General Information Caspase-9 (rat/mouse 454 aa; human 416-aa, also known as apoptotic protease activating factor 3 (APAF-3)/ICE-like apoptotic protease 6 or ICE-LAP6 or MCH-6, is involved in the activation cascade of caspases responsible for apoptosis execution. Binding of SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 25-aa peptide of human Caspase-9 (1); Designation (CASP91-P, control peptide). Epitope location ~ CT of p35 subunit SpCrossreactivity Human CASP91-P control peptide is 68% conserved in rat, 65% in mouse, 64% in xenopus, and 62% in chicken caspase-9. No significant sequence homology is detected with other caspases. Since CASP91-P Is located at the C-terminus of p35 subunit, the antibodies will not detect the p10 subunit. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.