Alpha Diagnostic International, Inc. Anti-Mouse Caspase 8 (ICE8/MACH/FLICE) antiserum #1 CASP81-S

Anti-Mouse Caspase 8 (ICE8/MACH/FLICE) antiserum #1 General Information Caspase-8, also known as (MACH, FADD-like ICE, FLICE, Mch-5, CAP4, MACH-alpha 1) human proenzyme is 479 aa (mouse 480 aa, rat 482 aa). It is the most upstream protease of the activation of caspases responsible for CD95 and TNFR-1 induced cell death. It SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 25-aa peptide within the p18 domain of mouse Caspase-8 (1); Designation (CASP81-P, control peptide). Epitope location ~ p18 domain SpCrossreactivity Mouse CASP81-P control peptide is 73% conserved in rat, and 57% in human caspase-8. No significant sequence homology is detected with other caspases. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.