Alpha Diagnostic International, Inc. Anti-Human Barttin antiserum BRTN11-S

Anti-Human Barttin antiserum General Information Bartter syndrome is an autosomal recessive disorder defined by hyokalemic metabolic alkalosis, elevated plasma renin activity and hyperaldosteronism with normal blood pressure and altered prostaglandin metabolism. Mutations in the NKCC2, K+-channel ROMK, SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 16-aa peptide of human Barttin; Designated (BRTN11-P or control peptide) conjugated to KLH; epitope location ~ N-terminal, Cytoplasmic domain SpCrossreactivity The BRTN11-P control peptide 100% conserved in mouse, rat, and human CLC-1. No significant sequence homology is detected with other CLCs or other proteins. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.