Alpha Diagnostic International, Inc. Human Barttin Control/blocking peptide BRTN11-P

Human Barttin Control/blocking peptide General Information Bartter syndrome is an autosomal recessive disorder defined by hyokalemic metabolic alkalosis, elevated plasma renin activity and hyperaldosteronism with normal blood pressure and altered prostaglandin metabolism. Mutations in the NKCC2, K+-channel ROMK, SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 16-aa peptide of human Barttin; Designated (BRTN11-P or control peptide) conjugated to KLH; epitope location ~ N-terminal, Cytoplasmic domain SpCrossreactivity The BRTN11-P control peptide 100% conserved in mouse, rat, and human CLC-1. No significant sequence homology is detected with other CLCs or other proteins. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.