Alpha Diagnostic International, Inc. Recombinant Human Brain Derived Neurotrophic Factor (BDNF) Protein BDNF11-R

Recombinant Human Brain Derived Neurotrophic Factor (BDNF) Protein General Information Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that includes NGF, NT-3, and NT-4 9also designated NT5). Human BDNF (mature protein 119 aa; chromosome 11p13) is produced from a 247 aa propeptide by the cl SpeciesReactivity Human Form Protein Pure Antigen Human brain BDNF (full length 119-aa, 13.6 kda, a dimer of ~27 kda) was expressed in E. coli purified to >97% purity (assessed by RP_HPLC, anion exchange FPLC, and SDS-PAGE). SpCrossreactivity Recombinant purified BDNF is fully biologically active when compared to standard. The ED50, calculated by the dose-dependant induction of ACHE (acetylcholine esterase) in rat basal forebrain primary septal culture is 50 ng/ml. For research use only, not for diagnostic or therapeutic use.