Alpha Diagnostic International, Inc. Human beta-3 Adrenergic receptor Control/blocking peptide # 1 B3AR11-P

Human beta-3 Adrenergic receptor Control/blocking peptide # 1 General Information The beta 3-adrenergic receptor (B3AR) is a member of the super-family of G protein-coupled receptors that are characterized by seven putative transmembrane helices connected by hydrophilic loops. The mechanism by which the activated beta ARs transmit the SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 19aa peptide of Human B3AR Designated (B3AR11-P or control peptide). Epitope location ~ C-terminus SpCrossreactivity The 19 AA human B3AR, splice form 3, immunogenic peptide sequence is 68% homologous with canine B3AR (13/19 AA), and human B3AR splice form 2. The human B3AR does not have significant homology with the mouse/rat B3AR. Anti-B3AR12 antibodies are not likely to crossreact with mouse/rat B3AR. Antibody crossreactivity in various species is not established. For research use only, not for diagnostic or therapeutic use.