Alpha Diagnostic International, Inc. Mouse/rat Aquaporin 2 (AQP2) Control/blocking peptide # 3 AQP23-P

Mouse/rat Aquaporin 2 (AQP2) Control/blocking peptide # 3 General Information AQP2 or AQP-CD or WCH-CD (mouse, rat, and human 271 aa; human gene locus 12q13) is the vasopressin-regulate d water channel of the apical membrane of collecting duct cells. AQP families of proteins are predicted to contain six transmembrane domains. The SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Mouse Form Antigen/blocking Peptide Antigen 19-aa peptide of Rat AQP2 (protein accession #P56402, refs 1); Designated (AQP21-P or control peptide /blocking peptide) conjugated to KLH; epitope location ~ N-terminal, Extracellular domain 2 SpCrossreactivity Mouse AQP23-P peptide is 100% conserved in rat, 78% in ovine, 73% in human AQP2. Antibody cross-reactivity in various species has not been studied. For research use only, not for diagnostic or therapeutic use.