Alpha Diagnostic International, Inc. Anti-Human Amyloid precursor protein (APP770) antiserum # 1 APP11-S

Anti-Human Amyloid precursor protein (APP770) antiserum # 1 General Information APP gene has 19 exons (1). At least 8 different types of APP (APP695, APP751, and APP770 are the major ones) are produced as a result of alternative splicing of exons 7, 8, and 15. Exons 7 codes for a 57-aa domain that is analogous to Kunitz protease in SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2477-seconda ry-antibodies-chicke n.htm SpeciesReactivity Human SugNegativeControl Non-immune Chicken IgG Cat# 20010-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 15aa peptide of Human APP770 ; Designated (APP11-P or control peptide). Epitope location ~ Mid-region, Extracellular SpCrossreactivity The human APP11-P peptide sequence is only found in APP that contains the KPI region (i.e., APP770 isoform). The APP11-P sequence is the same in mouse and rat APP770 isoforms. Antibody crossreactivity in various species is not established For research use only, not for diagnostic or therapeutic use.