Alpha Diagnostic International, Inc. Human APOBEC 1 Control/blocking peptide # 1 APOBEC11-P

Human APOBEC 1 Control/blocking peptide # 1 General Information Apobec-1, a 236aa protein in human (chr 12p13.1) an RNA specific cytidine deaminase, is essential but not efficient for apo B editing activity, there being a requirement for other protein factor. Apobec-1 is a dimer with the composite active site assemble SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 16-aa peptide from Human Apobec-1 (gene accession # P41238, refs 1); Designation (APOBEC11-P, control peptide); ~C-terminus SpCrossreactivity Human APOBEC11-P control peptide is 100% conserved in chimp, 93% in pongo pygmaeus, and 75% in rabbit. The eptioep is only partly (~50%) contained in mouse and rat APOBEC1. APOBEC-1. Antibody cross-reactivity in various species has not been studied. Control peptide, because of its low mol. Wt (<3 kDa), is not suitable for Western. It should be used for ELISA or antibody blocking experiments For research use only, not for diagnostic or therapeutic use.