Alpha Diagnostic International, Inc. Rat Anion Exchanger 1 (AE1) Control/blocking peptide #1 AE11-P

Rat Anion Exchanger 1 (AE1) Control/blocking peptide #1 General Information AE1 protein (also know as band 3) is the most abundant protein in red cell membrane. AE1 gene has been cloned and characterized from a variety of species including mouse, rat, human, and chicken. Human AE1 gene (chromosome 17q21-qter) encodes for a prot SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 20-aa peptide of from the ~ N-terminus Cytoplasmic region of Rat AE1/B3AT, Slc4a1 (protein accession # P23562, refs 1; Designated (AE11-P or Control peptide) SpCrossreactivity AE11-P control peptide is 85% conserved in mouse, 70% in human, and 75% in bovine AE1. AE11-P epitope is conserved in both isoform 1 (erythrocytes) and isoforms 2 (kidney). AE11-A antibodies should detect both forms. No significant sequence homology is detected with other AE or other proteins. Antibody crossreactivity in various other species is not established For research use only, not for diagnostic or therapeutic use.