Alpha Diagnostic International, Inc. Mouse Adiponectin receptor 1 (ADIPOR1) Control/blocking peptide # 2 ADIPOR12-P

Mouse Adiponectin receptor 1 (ADIPOR1) Control/blocking peptide # 2 General Information The adiponectin receptors, ADIPOR1 and ADIPOR2, serve as receptors for globular and full-length adiponectin and mediate increased AMPK and PPAR-alpha (PPARA) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin. ADIPOR1 an SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Mouse Form Antigen/blocking Peptide Antigen 18-aa peptide from Mouse ADIPOR1 (protein accession # Q3TI02, refs 1), designated ADIPOR12-P or Control Peptide/blocking peptide) conjugated to KLH; ~C-terminus, Extracellular domain SpCrossreactivity Mouse ADIPOR12-P is 100% conserved in rat, pig, green puffer, chicken, duck, bovine, 94% in human, chimp, zebra fish, and frog, ADIPOR1. No significant sequence homology is seen with ADIPOR2. Antibody crossreactivity in various other species is not established. The control peptide, because of its low mol. Wt (<3 kDa), is not suitable for Western. It should be used for ELISA or antibody blocking experiments (use 5-10 ug control peptide per 1 ug of aff pure IgG or 1 ul antiserum) to confirm antibody specificity For research use only, not for diagnostic or therapeutic use.