Alpha Diagnostic International, Inc. Human APOBEC complementation factor (ACF) Control/blocking peptide # 1 ACF11-P

Human APOBEC complementation factor (ACF) Control/blocking peptide # 1 General Information RNA editing is an important mechanism for regulating genetic plasticity through the generation of alternative protein products from a single structural gene. Substitutional RNA editing employs a variety of genetic mechanisms, the biochemical basis of whic SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 17-aa peptide from Human ACF (gene accession # Q9NQ94, refs 1); Designation (ACF11-P, control peptide) SpCrossreactivity The ACF11-P control peptide is 100% conserved in rat (isoforms-1-2), mouse (isoforms 2 ) and human (isoforms 1-6, ) and 88% in frog ACF. Since ACF11-P is located at the C-terminus, the antibodies are likely to react with most ACF isoforms 1-6. Antibody cross-reactivity in various species or isoforms has not been studied. Control peptide, because of its low mol. Wt (<3 kDa), is not suitable for Western. It should be used for ELISA or antibody blocking experiments For research use only, not for diagnostic or therapeutic use.