Alpha Diagnostic International, Inc. Anti-human APOBEC complementation factor (ACF) IgG, aff pure ACF11-A

Anti-human APOBEC complementation factor (ACF) IgG, aff pure General Information RNA editing is an important mechanism for regulating genetic plasticity through the generation of alternative protein products from a single structural gene. Substitutional RNA editing employs a variety of genetic mechanisms, the biochemical basis of whic SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 17-aa peptide from Human ACF (gene accession # Q9NQ94, refs 1); Designation (ACF11-P, control peptide) SpCrossreactivity The ACF11-P control peptide is 100% conserved in rat (isoforms-1-2), mouse (isoforms 2 ) and human (isoforms 1-6, ) and 88% in frog ACF. Since ACF11-P is located at the C-terminus, the antibodies are likely to react with most ACF isoforms 1-6. Antibody cross-reactivity in various species or isoforms has not been studied. Control peptide, because of its low mol. Wt (<3 kDa), is not suitable for Western. It should be used for ELISA or antibody blocking experiments For research use only, not for diagnostic or therapeutic use.