Anti-Human Angiotensin converting enzyme 1 (ACE-1) IgG # 2, aff pure
General Information
ACE (also known as dipeptidyl carboxypeptidase-1, DCP1; Kininase-II, ACE1) gene has been mapped at human chromosome 17q23. The s-ACE and t-ACE isoforms are generated by alternative splicing of ACE-2 gene. Somatic-ACE, a Zn (II) containing dipeptidyl carbo
SugApplications
Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the
SugSecAntibodies
http://4adi.com/comm
SpeciesReactivity
Human
SugNegativeControl
Non-immune Rabbit IgG Cat# 20009-1
Form
Affinity purified IgG
SugPositiveControl
Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid
Antigen
14-aa peptide of Human testicular-ACE (gene accession # P22966, refs 1); Designated (ACE12-P or control peptide); location: ~N-terminal, Extracellular
SpCrossreactivity
Human testicular ACE12-P control peptide is 92% conserved in mouse and 57% in rat t-ACE. ACE12-P epitope is located near the N-terminus that is found in membrane bound as well soluble t-ace. So the antibodies are expected to react with both isoforms. No significant sequence homology exist with the s-Ace of any species. Antibody cross-reactivity in various species is not known. Control peptide, because of its low mol. Wt (<3 kDa), is not suitable for Western. It should be used for ELISA or antibody blocking experiments (use 5-10 ug control peptide per 1 ug of aff pure IgG or 1 ul antiserum) to confirm antibody specificity
For research use only, not for diagnostic or therapeutic use.
| Alpha Diagnostic International, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | ACE12-A |
| Product Name | Anti-Human Angiotensin converting enzyme 1 (ACE-1) IgG # 2, aff pure |