Alpha Diagnostic International, Inc. Mouse Angiotensin converting enzyme 1 (ACE-1) control peptide # 1 ACE11-P

Mouse Angiotensin converting enzyme 1 (ACE-1) control peptide # 1 General Information ACE (also known as dipeptidyl carboxypeptidase-1, DCP1; Kininase-II, ACE1) gene has been mapped at human chromosome 17q23. The s-ACE and t-ACE isoforms are generated by alternative splicing of ACE-2 gene. Somatic-ACE, a Zn (II) containing dipeptidyl carbo SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Mouse Form Antigen/blocking Peptide Antigen Antigen: 15aa peptide of Mouse somatic-ACE (gene accession # P09470, refs 1); Designated (ACE11-P or control peptide) conjugated to KLH Location: ~Extracellar SpCrossreactivity Mouse somatic ACE11-P control peptide is 81% conserved in rat, 93% in pig, and 87% in human s-ACE. No significant sequence homology exist with the t-ace or ACE-2 of any species. Antibody (cat # ACE11-A) cross-reactivity in various species is not known. Control peptide, because of its low mol. Wt (<3 kDa), is not suitable for Western. It should be used for ELISA or antibody blocking experiments (use 5-10 ug control peptide per 1 ug of aff pure IgG or 1 ul antiserum) to confirm antibody specificity For research use only, not for diagnostic or therapeutic use.