Alpha Diagnostic International, Inc. Rat Acetyl-CoA Carboxylase-2 (ACC-2) Control/blocking peptide ACC21-P

Rat Acetyl-CoA Carboxylase-2 (ACC-2) Control/blocking peptide General Information ACC-2 (rat 2456-aa, human 2483-aa, ~280 kDa, chromosome 12q24.1), also known as ACC-beta, is predominantly present in heart and skeletal muscle and to a lesser extent in liver. An additional ACC-2 isoform (270 kDa) is present in liver. In contrast to AC SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 20-aa peptide of rat ACC2 (gene accession NP_446374 refs 1) ; Designated (ACC21-P or control/blocking peptide). SpCrossreactivity The rat ACC21-P peptide is 75% conserved in mouse and 60% in human ACC2. No significant sequence homology of ACC21-P is seen with ACC-1 or any other protein. Antibody reactivity in various species is not known. The ACC21-P control peptide, because of its low mol. Wt (<3 kDa), is not suitable for Western. It should be used for ELISA or antibody blocking experiments (use 5-10 ug control peptide per 1 ug of aff pure IgG or 1 ul antiserum) to confirm antibody specificity For research use only, not for diagnostic or therapeutic use.