Alpha Diagnostic International, Inc. Rat ATP binding cassette, subfamily G, member 5, (ABCG5) Control/blocking peptide # 2 ABCG52-P

Rat ATP binding cassette, subfamily G, member 5, (ABCG5) Control/blocking peptide # 2 General Information ABCG5/sterolin-1 gene product a 651aa residue in human, and 652aa each in rat and mouse, plays an important role in the selective transport of cholesterol in and out of the enterocytes and in the selective sterol excretion by liver into bile. Strongly exp SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 14-aa peptide from human ABCG5 (gene accession # Q99PE7, refs 1); Designation (ABCG52-P, control peptide /blocking peptide) SpCrossreactivity Rat ABCG52-P control peptide is 85% in mouse ABCG5. No significant conservation of ABCG31-P is observed with other ABCGs (ABCG1-4, 6) or other proteins. Antibody cross-reactivity in various species has not been studied. Control peptide, because of its low mol. Wt (<3 kDa), is not suitable for Western. It should be used for ELISA or antibody blocking experiments (use 5-10 ug control peptide per 1 ug of aff pure IgG or 1 ul antiserum) to confirm antibody specificity For research use only, not for diagnostic or therapeutic use.