Alpha Diagnostic International, Inc. Canine Adenosine receptor 2a (A2aR) Control/blocking peptide #1 A2aR21-P

Canine Adenosine receptor 2a (A2aR) Control/blocking peptide #1 General Information The purine nucleoside adenosine modulates diverse physiological functions including induction of sedation, vasodilatation, suppression of cardiac rate and contractility, neurotransmitter release, inhibition of platelet aggregation and lipolysis. Adenosine SugApplications Control peptide, because of its low mol. Wt (<3 kDa), is not suitable for Western. It should be used for ELISA or antibody blocking experiments (use 5-10 ug control peptide per 1 ug of aff pure IgG or 1 ul antiserum) to confirm antibody specificity SpeciesReactivity Canine Form Antigen/blocking Peptide Antigen Antigen: 30aa peptide of Rat A2aR/ADORA2A (Gene Accession # P11617) ; Designated (#A2aR21-P or control peptide) conjugated to KLH Location: ~C-terminus, Intracellular SugPositiveControl Brain, Kidney or other tissues or cells lines expressing the given adenosine receptor protein or Recombinant cells (bacterial or mammalian) with high level expression. SpCrossreactivity The canine A2aR21-P peptide is conserved 80% in human, 76% in chimp, horse, 72% in chicken, 71% in pig, 62% in rabbit, 43% in rat A2aR. Antibody to canine A2aR21-P has been shown to crossreact with human, bovine, rat, and pig A2a receptors. Control pept MSDS Contains no preservatives For research use only, not for diagnostic or therapeutic use.