A.G. Scientific, Inc. Novobiocin Sodium Salt N-1180

Description
Inhibitor of HSP90. Novobiocin interacts with the C-terminal ATP-binding domain of HSP90, unlike 17-AAG (A1256), Geldanamycin (G1047), Herbimycin A (H1050), or Radicicol (R1130) which all bind to the N-terminal ATP-binding site of HSP90. Also useful in production of positively supercoiled plasma DNA, targeting the nucleotide-binding site of gyrase B.
Description
Inhibitor of HSP90. Novobiocin interacts with the C-terminal ATP-binding domain of HSP90, unlike 17-AAG (A1256), Geldanamycin (G1047), Herbimycin A (H1050), or Radicicol (R1130) which all bind to the N-terminal ATP-binding site of HSP90. Also useful in production of positively supercoiled plasma DNA, targeting the nucleotide-binding site of gyrase B.

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San Diego, CA, USA
Novobiocin Sodium Salt
N-1180
Novobiocin Sodium Salt N-1180
Inhibitor of HSP90. Novobiocin interacts with the C-terminal ATP-binding domain of HSP90, unlike 17-AAG (A1256), Geldanamycin (G1047), Herbimycin A (H1050), or Radicicol (R1130) which all bind to the N-terminal ATP-binding site of HSP90. Also useful in production of positively supercoiled plasma DNA, targeting the nucleotide-binding site of gyrase B.

Inhibitor of HSP90. Novobiocin interacts with the C-terminal ATP-binding domain of HSP90, unlike 17-AAG (A1256), Geldanamycin (G1047), Herbimycin A (H1050), or Radicicol (R1130) which all bind to the N-terminal ATP-binding site of HSP90. Also useful in production of positively supercoiled plasma DNA, targeting the nucleotide-binding site of gyrase B.

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Organic Chemicals
Product Number N-1180
Product Name Novobiocin Sodium Salt
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