Erlotinib is an inhibitor of human Epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 2 nM) and decreases EGFR autophosphorylation in tumor cells (IC50 = 20 nM). Studies in cell lines and enzyme assays have both shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl.
| A.G. Scientific, Inc. | |
|---|---|
| Product Category | Organic Chemicals |
| Product Number | E-2307 |
| Product Name | Erlotinib, Hydrochloride Salt |
| Trigger | Salt |
| Chemical Name | CP-358774, OSI-774 |
| Chemical Formula | C22H23N3O4.HCl |
