Gelest, Inc. 1,4-DIVINYL-1,1,4,4-TETRAMETHYL-1,4-DISILABUTANE SID4614.0

Additional Properties Hydrolytic Sensitivity 1: no significant reaction with aqueous systems Application Intermediate for curare analogs.1 Potential vinyl nucleophile in cross-coupling reactions.2 Reference 1. Tacke, R. et al. Z. Naturforsch., B: Anorg. Chem., Org. Chem. 1982, 37B, 1461. 2. Larson, G. L. “Silicon-Based Cross-Coupling Reagents” Gelest, Inc. 2011. Safety Packaging Under Nitrogen Alkenylsilane Cross-Coupling Agent The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile. 1,4-Divinyl-1,1,4,4- tetramethyl-1,4-disi labutane; Bis(ethenyldimethyls ilyl)ethane Potential vinyl donor in cross-coupling reactions Intermediate for curare analogs Potential vinyl nucleophile in cross-coupling reactions Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011