Additional Properties
Hydrolytic Sensitivity 7: reacts slowly with moisture/water Safety
Packaging Under Nitrogen Trialkylsilyl Blocking Agent Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure. N,N-Dimethylaminotri
ethylsilane; Triethylsilyldimethy
lamine
Very reactive triethylsilyl protecting group
Dimethylamine by-product produced
Used primarily for the protection of alcohols
Can be used to protect amines and carboxylic acids
Summary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure
Gelest, Inc.
Done
Datasheet
Description
Additional Properties
Hydrolytic Sensitivity 7: reacts slowly with moisture/water Safety
Packaging Under Nitrogen Trialkylsilyl Blocking Agent Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure. N,N-Dimethylaminotri
ethylsilane; Triethylsilyldimethy
lamine
Very reactive triethylsilyl protecting group
Dimethylamine by-product produced
Used primarily for the protection of alcohols
Can be used to protect amines and carboxylic acids
Summary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure
Additional Properties
Hydrolytic Sensitivity 7: reacts slowly with moisture/water Safety
Packaging Under Nitrogen Trialkylsilyl Blocking Agent Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure. N,N-Dimethylaminotri
ethylsilane; Triethylsilyldimethy
lamine
Very reactive triethylsilyl protecting group
Dimethylamine by-product produced
Used primarily for the protection of alcohols
Can be used to protect amines and carboxylic acids
Summary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure
Additional Properties
Hydrolytic Sensitivity 7: reacts slowly with moisture/water
Safety
Packaging Under Nitrogen
Trialkylsilyl Blocking Agent
Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.
N,N-Dimethylaminotriethylsilane; Triethylsilyldimethylamine
Very reactive triethylsilyl protecting group
Dimethylamine by-product produced
Used primarily for the protection of alcohols
Can be used to protect amines and carboxylic acids
Summary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure
