Mouse monoclonal Tollip antibody
Background:
Toll interacting protein, also known as Tollip, is an inhibitory adaptor protein within the signaling pathway of IL-1 and Toll-like receptors(TLR). The Toll-like receptors are essential transmembrane signaling receptors of the innate immune system that alert the host to the presence of a microbial invader. Tollip recruits IRAk1 to the IL-1 receptor complex and inhibits IRAk1 phosphorylation and kinase activity.
| Fitzgerald Industries International, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | 10R-1116 |
| Product Name | Tollip antibody |