Mouse monoclonal TMEFF2 antibody
Background:
TMEFF2 (transmembrane protein with EGF-like and two follistatin-like domains 2), a gene encoding a plasma membrane protein with two follistatin-like domains and one epidermal growth factor-like domain, had limited normal tissue distribution and was highly overexpressed in prostate cancer. The shedded form up-regulates cancer cell proliferation, probably by promoting ERk1/2 phosphorylation. Down-regulated in tumor cell lines in response to a high level of methylation in the 5' region.
| Fitzgerald Industries International, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | 10R-1113 |
| Product Name | TMEFF2 antibody |
